John Edwards, a Democratic former senator, vice presidential nominee and two-time presidential candidate, has been indicted on charges that he used campaign contributions to hide an extramarital affair. (Steve Exum/Getty)
Rep. Mark Souder (R-Ind.) resigned in 2010 after it was revealed he had an extramarital affair with a staffer. (Tom Williams/Getty)
Rep. Eric Massa (D-N.Y.) resigned in 2010 during an ethics investigation into sexual harassment charges involving a male staffer. (Chip Somodevilla/Getty)
Rep. Vito Fossella (R-N.Y.) did not seek reelection in 2008 after a drunk driving conviction and revelations of an extramarital affair in which he fathered a child. (Tom Williams/Getty)
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Rep. Tim Mahoney (D-Fla.) lost his reelection in 2008 after it was revealed that he had put a former mistress on his staff. Mahoney had succeeded GOP Rep. Mark Foley, who resigned two years earlier amid scandal. (Joe Raedle/Getty Images)
New Jersey Gov. James E. McGreevey, a Democrat, resigned in 2004 after acknowledging an extramarital affair with another man. (William Bird/Getty)
Sen. David Vitter (R-La.) was linked to an escort service scandal in 2007. He acknowledged his misbehavior and was reelected in 2010. (Bill Clark/Getty)
Sen. Larry Craig (R-Idaho) pleaded guilty to disorderly conduct in an airport restroom and was admonished by the Senate Ethics Committee. He resisted calls to resign, but did not seek reelection in 2008. (Manuel Balce Ceneta / Associated Press)
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Republican South Carolina Gov. Mark Sanford revealed an extramarital affair in 2009. State lawmakers rejected impeachment, but recommended a formal rebuke related to state funds he spent for travel related to the affair. He served out the remainder of his second term, which expired in January 2011. (Davis Turner/Getty)
Republican Jack Ryan abandoned his 2004 campaign for a Senate seat in Illinois after allegations in a divorce case that he had taken his wife -- actress Jeri Ryan, whom he divorced in 1999 -- to sex clubs. Barack Obama was elected to the Senate seat. (Scott Olson/Getty)
Rep. Gary Condit (D-Calif.) lost his reelection primary in 2002 after it was revealed he had an extramarital affair with intern Chandra Levy, who disappeared in 2001 and was found slain a year later. A Salvadoran immigrant was convicted of killing her. (Stephen J. Boitano / Associated Press)
Gary Hart, a former Colorado senator, lost his 1988 bid for the Democratic presidential nomination amid revelations he had had an extramarital affair. (Ed Andrieski / Associated Press)